Arava (leflunomide)

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LeflunomideInformation :

ARAVA is indicated in adults for the treatment of active rheumatoid arthritis (RA):

• to reduce signs and symptoms


• to inhibit structural damage as evidenced by X-ray erosions and joint space narrowing


• to improve physical function

INSTRUCTIONS 

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

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The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

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STORAGE

Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F). Protect from light. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Store the medicine in a closed container at room temperature, away from heat, moisture.

 Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Store the medicine in a closed container at room temperature, away from heat, moisture.

SIDE EFFECTS OF Arava (leflunomide)

In addition to its needed effects, some unwanted effects may be caused by leflunomide. In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking leflunomide:

More common

• Bloody or cloudy urine
• cough
• difficult or painful breathing
• difficult, burning, or painful urination
• dizziness
• fever
• frequent urge to urinate
• headache
• loss of appetite
• nausea or vomiting
• sneezing
• sore throat
• tightness in the chest
• yellow eyes or skin

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Less common

• Burning feeling in the chest or stomach
• burning, prickling, or tingling sensation in the fingers or toes
• chest pain
• diarrhea
• fast heartbeat
• indizestion
• joint or muscle pain or stiffness
• pounding heartbeat
• severe stomach pain

Incidence not known

• Area rash
• black or tarry stools
• bleeding gums
• blistering, peeling, or loosening of the skin
• bloating
• blood in the stools
• burning, numbness, tingling, or painful sensations
• chills
• clay-colored stools
• confusion
• constipation
• continuing vomiting
• cough or hoarseness
• dark urine
• fainting
• fever with or without chills
• general feeling of tiredness or weakness
• high fever

Some of the side effects that can occur with leflunomide may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Depo Provera (Medroxyprogesterone acetate)

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Depo-Provera (Medroxyprogesterone acetate)

Depo-Provera CI is indicated only for the prevention of pregnancy. The loss of bone mineral density (BMD) in women of all ages and the impact on peak bone mass in adolescents should be considered, along with the decrease in BMD that occurs during pregnancy and/or lactation

Prevention Of Pregnancy

Both the 1 mL vial and the 1 mL prefilled syringe of Depo-Provera CI should be vigorously shaken just before use to ensure that the dose being administered represents a uniform suspension. The recommended dose is 150 mg of Depo-Provera CI every 3 months (13 weeks) administered by deep IM injection in the gluteal or deltoid muscle. Depo-Provera CI should not be used as a long-term birth control method (i.e. longer than 2 years) unless other birth control methods are considered inadequate. Dosage does not need to be adjusted for body weight [see Clinical Studies].

To ensure the patient is not pregnant at the time of the first injection, the first injection should be given ONLY during the first 5 days of a normal menstrual period; ONLY within the first 5-days postpartum if not breast-feeding; and if exclusively breast-feeding, ONLY at the sixth postpartum week. If the time interval between injections is greater than 13 weeks, the physician should determine that the patient is not pregnant before administering the drug. The efficacy of Depo-Provera CI depends on adherence to the dosage schedule of administration.

The following important adverse reactions observed with the use of Depo-Provera CI are discussed in greater detail in the Warnings and Precautions section (5):

• Loss of Bone Mineral Density [see WARNINGS AND PRECAUTIONS]
• Thromboembolic disease [see WARNINGS AND PRECAUTIONS]
• Breast Cancer [see WARNINGS AND PRECAUTIONS]
• Anaphylaxis and Anaphylactoid Reactions [see WARNINGS AND PRECAUTIONS]
• Bleeding Irregularities[see WARNINGS AND PRECAUTIONS]
• Weight Gain [see WARNINGS AND PRECAUTIONS]

CLINICAL TRIALS EXPERIENCE

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

WARNING: This medication may cause serious bone loss. The risk of bone loss increases with longer use of this medication. This bone loss may be permanent even after you stop using medroxyprogesterone injection. This medication should not be used for longer than 2 years unless other birth control methods will not work for you. The years of adolescence and early adulthood are important for your body to build healthy bones. Use of this medication may increase the risk of broken bones when you are older. Discuss with your doctor the risks and benefits of this medication and other birth control choices.

Keep all your medical/lab appointments. Your doctor may test your bone density while you are using this medication. Be sure to get enough vitamin D and calcium in your diet. Consult your doctor or pharmacist to determine whether you need calcium/vitamin D supplements to help keep your bones healthy.

Use of this medication does not protect you against sexually transmitted diseases (e.g., HIV, hepatitis B, gonorrhea). Consult your doctor or pharmacist if you have any questions.

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Levora Buy Online

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Levora is a popular drug thatcontains a great combination of several female sex hormones that are known to help in the prevention of ovulation.

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Levora Information

Levora is a popular drug thatcontains a great combination of several female sex hormones that are known to help in the prevention of ovulation. This medicine is also known to cause various changes in the woman’s uterine lining and cervical mucous, thus making it harder for a fertilized egg to attach itself to the woman’s uterus. Levora is widely prescribed as a contraceptive and it is taken by woman as who want to prevent an unwanted pregnancy.

Levora Indications

Levora is a popular contraceptive method (pill) that is often taken by patients (women) who want to avoid the risk of an unwanted pregnancy. However, this drug could also be prescribed to treat or to prevent some other medical disorders that have not been mentioned here.

Levora Warnings

A treatment with this medicine during pregnancy is known to cause severe (dangerous) birth defects. It is recommended that you use an extra birth control method. If you accidentally get pregnant during your treatment with this drug, you must alert your personal doctor right away. You should wait at least one month after you have had a baby to start a treatment with this medicine. You should not start a treatment with Levora if you have:

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• a history of blood clot or stroke;
• circulation problems;
• a cancer that is hormone-related such as uterine or Breast Cancer;
• seizures such as epilepsy;
• unusual vaginal bleeding;
• liver disorder (this also includes liver cancer);
• dangerously high blood pressure;
• severe headaches;
• a history of irregular menstrual periods;
• a history of jaundice that may have been caused by the intake of other birth control pills;
• a heart valve disease.

If you do have any of the medical disorders that have been mentioned here, you may have to take in a lower dose of Levora (or you might not be allowed to start a treatment with this medicine at all). The hormones that are found in most birth control pills are known to be able to pass into the patient’s breast milk, thus harming a nursing infant. A treatment with this drug is also known to decrease the organism’s regular milk production. You must not start a treatment with this medicine if you are currently breastfeeding a child.

A treatment with a hormone-based medicine is known to increase the patient’s (woman’s) risk of developing stroke, blood clots, heart attack or other heart disorders (especially if the patient is older than 35 year old or if she is a smoker).

Levora Intake Guidelines

Ask your personal doctor how and when you should take Levora. You must not disobey any of his or her instructions (advices). You can also rely on the instructions that are usually written on the drug’s label. If you do not understand some of these instructions, you can ask a nurse, a doctor or a pharmacist for further advice and recommendations (they should be able to explain them to you).

Levora Dosage

Ask your personal physician to tell you the proper dose of Levora that you should take during your treatment with this drug. Avoid altering the dose that he or she has prescribed you in any way without your physician’s consent. The regular dose of Levora normally consists of one pill that should be taken once each day. When you have no more tablets in your pack, buy another pack of pills and start it the following day.

Levora Overdose

If you think that you might be suffering from an overdose with this drug, you are in need for immediate medical attention. You should contact your local poison control centre as soon as you can. Inform your personal physician immediately. The average symptoms of an overdose with Levora usually include vomiting, nausea and vaginal bleeding.

Levora Missed Dose

Missing one or more of your prescribed doses of this drug could increases the risk of getting pregnant. If you miss even one if your prescribed doses of Levora, you should contact your personal physician and ask him or her for further instructions..

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