Showing posts with label antidepressants-and-pregnancy. Show all posts
Showing posts with label antidepressants-and-pregnancy. Show all posts

Sunday, 15 January 2017

Atarax (Hydroxyzine)

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Atarax Information
Atarax is made by Pfizer and is generically known as hydroxyzine hydrochloride and is available in tablet and syrup form.

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Atarax Indications
Atarax is prescribed for the relief of anxiety and tension brought about by psychoneurosis.
Atarax may also be used for the containment of pruritus due to allergic reactions such as chronic uticaria and contact dermatitis.
Atarax may be used as a sedative when used as a premedication following general anesthesia.

Atarax Warnings
Studies of Atarax in pregnant humans have not yet been studied however, studies on animals have shown that Atarax induce fetal abnormalities in pregnant mice, rabbits and other animals.
It is not also known whether the contents of Atarax are passed into human milk. Talk with your doctor first before considering breast feeding.
Drowsiness is a main consideration when taking this drug and activities such as driving or operating machinery should be avoided.
Patients are also not advised to repeatedly take CNS depressant drug such as this.

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Atarax Intake Guidelines
Follow your doctor’s instructions when taking Atarax. Never deviate from the doctor’s instructed intake instructions.

Atarax Dosage
For the treatment of anxiety and tension, the dose is 50-100 mg for adults, 50 mg daily divided into two doses for children.
For the management of pruritus, the dosage for adults is 25 mg and for children, it is 50 mg divided in two doses.
For the usage of Atarax as a sedative, the dose is 50-100 mg in adults and 0.6mg/kg in children.
The dosage described above may be increased or decreased depending on your doctor’s assessment.

Atarax Overdose
The most common symptom of Atarax overdose is hypersedation. If overdose happens, the patient should be made to vomit, if he/she has no urge to vomit, it should be induced. Another relief is to immediate gastric lavage. Immediately seek emergency medical attention while continuing to monitor the patient’s vital signs.

Atarax Missed Dose
If a dose of Atarax is missed, never attempt to take double doses to make up for it. You may however, skip that dose you missed and just proceed with your regular time of intake.

Atarax Side Effects
The reported side effects associated with Atarax intake were usually mild and passing and are not causes for immediate medical care.
Among the side effects are dry mouth, drowsiness, and tremors.

Atarax Drug Reactions
There are no known harmful drug interactions associated with Atarax intake. But it is still best to tell your doctor of the medicines you are taking and have taken for the past week.

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In some countries ATARAX may also be known as: Alamon, Atazina, Durrax, Orgatrax, Quiess, Sedaril, Vistaril, Hydroxyzine, Ataraxone, Hyderax, Hixizine, Prurizin, Dalun, Fasarax, AH 3 N, Elroquil N, Iremofar, Qualidrozine, Otarex, Serecid, Iterax, Neurax, Phymorax, Abacus, Allerax, Antizine, Atano, Cerax, Drazine, Hadarax, Histan, Hizin, Honsa, Katrax, Validol, Ucerax, Neucalm 

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Friday, 13 January 2017

Keppra (Levetiracetam)

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Keppra is used to treat partial onset seizures in adults and children who are at least 1 month old.
It is also used to treat tonic-clonic seizures in adults and children who are at least 6 years old, and myoclonic seizures in adults and children who are at least 12 years old.

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INSTRUCTIONS


Take Keppraexactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.



Your doctor may occasionally change your dose to make sure you get the best results.



Keppra is usually taken twice per day. Take the medicine at the same time each day. You may take Keppra with or without food.



Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time.

Use Keppra regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Do not stop using Keppra without first talking to your doctor, even if you feel fine. You may have increased seizures if you stop using this medicine suddenly. You may need to use less and less before you stop the medication completely.

Seizures are often treated with a combination of different drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. .

Wear a medical alert tag or carry an ID card stating that you take Keppra. Any medical care provider who treats you should know that you take seizure medication.

To be sure Keppra is not causing harmful effects, your kidney function may need to be tested. Visit your doctor regularly.
If you missed a dose - take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


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DOSAGE



Important Administration Instructions



Keppra is given orally with or without food. The Keppra dosing regimen depends on the indication, age group, dosage form (tablets or oral solution), and renal function.



Prescribe the oral solution for pediatric patients with body weight ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with body weight above 20 kg.



When using the oral solution in pediatric patients, dosing is weight-based (mg per kg) using a calibrated measuring device (not a household teaspoon or tablespoon).
Keppra tablets should be swallowed whole. Keppra tablets should not be chewed or crushed.

Pediatric Patients

·         1 Month To 6 Months
Treatment should be initiated with a daily dose of 14 mg/kg in 2 divided doses (7 mg/kg twice daily). The daily dose should be increased every 2 weeks by increments of 14 mg/kg to the recommended daily dose of 42 mg/kg (21 mg/kg twice daily). In the clinical trial, the mean daily dose was 35 mg/kg in this age group. The effectiveness of lower doses has not been studied.

·         6 Months To 4 Years
Treatment should be initiated with a daily dose of 20 mg/kg in 2 divided doses (10 mg/kg twice daily). The daily dose should be increased in 2 weeks by an increment of 20 mg/kg to the recommended daily dose of 50 mg/kg (25 mg/kg twice daily). If a patient cannot tolerate a daily dose of 50 mg/kg, the daily dose may be reduced. In the clinical trial, the mean daily dose was 47 mg/kg in this age group.

·         4 Years To 16 Years

Treatment should be initiated with a daily dose of 20 mg/kg in 2 divided doses (10 mg/kg twice daily). The daily dose should be increased every 2 weeks by increments of 20 mg/kg to the recommended daily dose of 60 mg/kg (30 mg/kg twice daily). If a patient cannot tolerate a daily dose of 60 mg/kg, the daily dose may be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.



For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment should be initiated with a daily dose of 500 mg given as twice daily dosing (250 mg twice daily). The daily dose should be increased every 2 weeks by increments of 500 mg to a maximum recommended daily dose of 1500 mg (750 mg twice daily).



For Keppra tablet dosing in pediatric patients weighing more than 40 kg, treatment should be initiated with a daily dose of 1000 mg/day given as twice daily dosing (500 mg twice daily). The daily dose should be increased every 2 weeks by increments of 1000 mg/day to a maximum recommended daily dose of 3000 mg (1500 mg twice daily).



Partial Onset Seizures



Adults 16 Years And Older



In clinical trials, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were shown to be effective. Although in some studies there was a tendency toward greater response with higher dose [see Clinical Studies], a consistent increase in response with increased dose has not been shown.



Treatment should be initiated with a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Additional dosing increments may be given (1000 mg/day additional every 2 weeks) to a maximum recommended daily dose of 3000 mg. Doses greater than 3000 mg/day have been used in open-label studies for periods of 6 months and longer. There is no evidence that doses greater than 3000 mg/day confer additional benefit.


Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy


Treatment should be initiated with a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Dosage should be increased by 1000 mg/day every 2 weeks to the recommended daily dose of 3000 mg. The effectiveness of doses lower than 3000 mg/day has not been studied.



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Primary Generalized Tonic-Clonic Seizures



Adults 16 Years And Older

Treatment should be initiated with a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Dosage should be increased by 1000 mg/day every 2 weeks to the recommended daily dose of 3000 mg. The effectiveness of doses lower than 3000 mg/day has not been adequately studied.



Pediatric Patients Ages 6 To< 16 Years


Treatment should be initiated with a daily dose of 20 mg/kg in 2 divided doses (10 mg/kg twice daily). The daily dose should be increased every 2 weeks by increments of 20 mg/kg to the recommended daily dose of 60 mg/kg (30 mg/kg twice daily). The effectiveness of doses lower than 60 mg/kg/day has not been adequately studied. Patients with body weight ≤ 20 kg should be dosed with oral solution. Patients with body weight above 20 kg can be dosed with either tablets or oral solution. Only whole tablets should be administered.



Adult Patients With Impaired Renal Function


Keppra dosing must be individualized according to the patient's renal function status.

STORAGE
Store Keppra at room temperature away from moisture, heat, and light.

Side effects

·     Get emergency medical help if you have any of these signs of an allergic reaction to Keppra: hives; difficult breathing; swelling of your face, lips, tongue, or throat.



Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.



Call your doctor at once if you have a serious side effect such as:
  • hallucinations, unusual thoughts or behavior;
  • bruising, severe tingling, numbness, pain, muscle weakness;
  • feeling very weak or tired;
  • fever, chills, body aches, flu symptoms, sores in your mouth and throat;
  • problems with walking or movement;
  • the first sign of any skin rash, no matter how mild; or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
·         Less serious Keppra side effects may include:
  •  mild dizziness or drowsiness;
  • mild tired feeling;
  • loss of appetite; or
  • stuffy nose.

·    This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

Thursday, 12 January 2017

Dilantin (phenytoin)

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Dilantin (phenytoin)
Dilantin Information


Dilantin is approved for use as an anti-seizure medication (anticonvulsant), especially to prevent tonic-clonic (grand mal) seizures and complex partial seizures (psychomotor seizures). It may be used alone or with Phenobarbital or other anticonvulsants.

Dilantin Warnings

Dilantin can increase the metabolism (elimination) of many drugs, reducing their concentrations in the body. Drugs that may be affected include: digoxin, carbamazepine, clonazepam, corticosteroids (e.g.prednisone), cyclosporine, disopyramide, doxycycline, estrogens, felodipine, levodopa, lidocaine, methadone, mexiletine, oral contraceptives, paroxetine, quinidine, tacrolimus, theophylline, phenobarbital, and warfarin. Dilantin can interact with these drugs not only when it is added to therapy but also when it is discontinued. In the latter case, the concentration of the other drugs may increase. 

Dilantin's metabolism may be affected by other drugs. Drugs that can reduce the amount of Dilantin in the body include rifampin and phenobarbital. Drugs that increase Dilantin concentrations include Amiodarone, chloramphenicol,cimetidine, disulfiram, fluconazole, fluoxetine, isoniazid (INH), omeprazole, and paroxetine. 

Thus, measuring levels of Dilantin in the blood may be necessary when patients begin or discontinue other medications. There appears to an increased risk of malformations and birth defects in women taking Dilantin . 
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Thus Dilantin should be used in pregnancy only if the physician feels that the potential benefit outweighs the risk. Dilantin is secreted into breast milk. Nursing is not recommended for persons taking Dilantin .

Dilantin Side effects

Many varied adverse effects can occur during Dilantin therapy including dizziness, drowsiness, difficulty focusing (vision), unsteady gate, tiredness, abnormal involuntary movements, nausea, vomiting, constipation, abdominal pain, and loss of appetite. Children and young adults can develop overgrowth of the gums during long-term therapy which requires regular treatment by a dentist. 

Good oral hygiene and gum massage may reduce the risk. Rashes can occur in between 1 in 20 and 1 in 10 persons; some may be severe. Also, dark coloration of the skin may develop Dilantin can produce unusual growth of hair in some patients. This reaction most commonly affects the arms and legs but can also affect the trunk and face; it may be irreversible. Various lymph node reactions have been reported with Dilantin therapy. Lymph nodes may swell up, sometimes painfully. Dilantin may cause serum glucose to rise. 

Thus, blood sugar should be monitored closely when Dilantin is administered to patients with diabetes. Dilantin can potentially injure the liver although this is an uncommon occurrence. Dilantin can cause the platelet or white blood cell counts to drop, increasing the risk of bleeding or infection, respectively. Dilantin also can cause anemia. Because it interferes with vitamin D metabolism, Dilantin can cause weakening of the bones (osteomalacia). Dilantin can cause sexual dysfunction including decreased libido, impotence, and priapism (painful, prolonged erections).

Dilantin Overdose


If overdose is suspected, contact your local poison control center or emergency room immediately.

Wednesday, 11 January 2017

Norpress (Nortriptyline)

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Norpress Information

The active substance of Norpress, namely Nortriptyline Hydrochloride, belongs to the tricyclic antidepressants class of medication. Its mechanism of action consists of an alteration of the chemical imbalance that may appear in parts of the patient’s brain, an imbalance that causes several physical or emotional symptoms that affect the patient’s general health condition and quality of life. Norpress has a strong positive effect on correcting this imbalance thus effectively treating these symptoms.

Norpress Indications

Norpress is typically used for the treatment of patients that suffer from depression, as it effectively treats the symptoms of this affection and improves the patients’ general condition. Apart from that, Norpress may also be successfully employed as part of the smoking cessation therapy, as it helps fight the withdrawal effects and as such may aid patients who wish to quit smoking. There are other uses for this medicine that are not listed here. If your prescriber advises you to follow a therapy course with this medicine and you are not sure why, it is best to ask him or her for more information.

Norpress Warnings

Norpress may not be administered to children or adolescents, or to patients that have recently suffered from heart attack. Individuals that are allergic to any of the active or inactive substances in this drug, or to any other tricyclic antidepressants or patients that are following a treatment with MAO inhibitors may not start taking Norpress.

Other medical conditions may influence your ability to start a treatment with Norpress. You should seek the advice of your physician if you have any liver, heart or kidney disorders, seizure disorders such as epilepsy, if you have diabetes, glaucoma, or hyperthyroidism (or if you are taking any thyroid gland related medication). 

Patients that are pregnant or breastfeeding, patients that have sustained heavy brain damage or head trauma, patients with bipolar disorders or mania, heavy drinkers or suicidal patients may require special consideration before starting to take this drug. Electroshock therapy and medication such as stimulants or sedatives may also interfere with the possibility of starting a treatment with Norpress. You should inform your prescriber of any other medical condition you are suffering from before receiving a prescription for this pharmaceutical product.

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Norpress Intake Guidelines

Your prescriber will provide you with a complete set of guidelines for taking Norpress in order to achieve the best results from the therapy. It is best that you closely follow the prescriber’s indications. If the intake guidelines you are provided differ from any of the following information, you should take the drug as advised by your doctor.
The Norpress tablets need to be taken whole, without crushing or chewing them. You may take them with food or with a full glass of water. In some situations, the prescriber may recommend you to use just half a tablet at a time – this is only possible for the 25 mg tablets. The smoking cessation treatment typically lasts for 3 to 6 months, while the treatment for depression may last much longer. You should continue taking the tablets for the full duration of the therapy, although you may experience an improvement in your condition much sooner. Do not stop taking this medicine without your prescriber’s consent.

Norpress Dosage

For smoking cessation, the usual starting Norpress dosage is of 25 mg per day increasing in time to a maximum of 75 mg to 100 mg per day. The treatment should begin two to four weeks before the date you actually stop smoking. If the drug is employed for the treatment of depression, the treatment usually consists of three to four daily intakes of 25 mg each. Elderly patients will receive a lower daily dose than the adult one, for example 25 to 50 mg. Your prescriber may advise you to use a different Norpress dose than stated above. In this case, you should take the medication dosage that you have been prescribed.

Norpress Overdose

An overdose with Norpress is often a severe condition and requires prompt medical attention. As such, if you think that you may have taken too much of the medicine you should immediately contact the local poisons center or call your personal health care professional. In severe cases you may need to go to the nearest clinic or hospital in order to receive emergency medical assistance.
Norpress Missed Dose

You should keep a strict intake schedule for your Norpress doses, as this may help reduce the chances of accidentally missing any intakes. However, if you happen to miss a dose of the medicine, it is best that you completely skip taking it. Do not attempt to make up for the missed dose by taking a larger dose of the medicine. It is recommended that you continue taking the medicine as regular, but you should inform your personal physician in order to determine if any corrective measures need to be taken.

Norpress Side Effects

Norpress may cause a number of severe adverse reactions such as fainting, fits and seizures, severe chest pain, suicidal thoughts or allergic reactions. If you experience any of these you should immediately stop taking the drug and contact a trained health care professional. Other serious side effects of this medicine include jaundice, vision disturbances, heart beat disorders, hallucinations or confusion, anxiety, agitation or a worsening of the depression. You should inform your personal physician of these and any other unwanted effects that may appear during your Norpress treatment.

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Norpress Drug Reactions

Norpress may cause accidental drug reactions with other antidepressants (either tricyclic antidepressants, MAO inhibitors or SSR inhibitors), blood pressure medication, anticholinergics, sympathomimetics, thyroid medications, some heart drugs, Carbamazepine or Cimetidine. You should inform your prescriber of any other pharmaceutical products you are taking before starting your Norpress therapy.


Tuesday, 10 January 2017

Anafranil (Clomipramine HCL)

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What is Generic Anafranil (Clomipramine HCL)?


Generic Anafranil (Clomipramine HCL) is a tricyclic antidepressant. It affects chemicals in the brain that may become unbalanced.Generic Anafranil(Clomipramine HCL) is used to treat symptoms of obsessive-compulsive disorder (OCD) such as recurrent thoughts or feelings and repetitive actions.Generic Anafranil (Clomipramine HCL) may also be used for purposes other than those listed in this medication guide.




What is the most important information I should know about Generic Anafranil (Clomipramine HCL)?


Do not use this medication if you have recently had a heart attack, or if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Do not use Generic Anafranil(Clomipramine HCL) if you are allergic to it or to similar drugs such as amitriptyline (Elavil, Etrafon), amoxapine (Ascendin), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil),nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil). 

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. 

What should I discuss with my healthcare provider before taking Generic Anafranil (Clomipramine HCL)?


Do not use this medication if you are allergic to Generic Anafranil (Clomipramine HCL) or to similar drugs such as amitriptyline (Elavil, Etrafon), amoxapine (Ascendin), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil). 

Do not use Generic Anafranil (Clomipramine HCL) if you have recently had a heart attack, or if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take Generic Anafranil (Clomipramine HCL) before the MAO inhibitor has cleared from your body. 


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Before taking Generic Anafranil (Clomipramine HCL),

 tell your doctor if you are allergic to any drugs, or if you have:heart disease or a history of heart attack, stroke, or seizures;bipolar disorder (manic-depression), schizophrenia or other mental illness;kidney or liver disease; overactive thyroid or adrenal gland tumor (pheochromocytoma);glaucoma; orproblems with urination.If you have any of these conditions, you may not be able to use Generic Anafranil (Clomipramine HCL), or you may need a dosage adjustment or special tests during treatment.

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Tell your doctor if you have worsening symptoms of depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

How should I take Generic Anafranil (Clomipramine HCL)?


Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Your doctor may occasionally change your dose to make sure you get the best results from this medication. Follow the directions on your prescription label.Take Generic Anafranil (Clomipramine HCL) with food to reduce stomach upset. If you need to have any type of surgery, tell the surgeon ahead of time that you are taking Generic Anafranil (Clomipramine HCL). 

You may need to stop using the medicine for a short time.Do not stop using Generic Anafranil (Clomipramine HCL) without first talking to your doctor. You may need to use less and less before you stop the medication completely. It may take up to 4 weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 4 weeks of treatment. 

Store Generic Anafranil (Clomipramine HCL) at room temperature away from moisture and heat. 

What happens if I miss a dose?


Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Generic Anafranil (Clomipramine HCL) can be fatal. Symptoms may include fast or uneven heart rate, extreme drowsiness, confusion, agitation, vomiting, blurred vision, sweating, muscle stiffness, increased or decreased urination, swelling, shortness of breath, blue lips or fingernails, feeling light-headed, fainting, seizure (convulsions), or coma. 



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What should I avoid while taking Generic Anafranil (Clomipramine HCL)?

Avoid drinking alcohol. It can cause dangerous side effects when taken together with Generic Anafranil (Clomipramine HCL). Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, medicine for seizures, or other antidepressants). They can add to sleepiness caused by Generic Anafranil (Clomipramine HCL).Grapefruit and grapefruit juice may interact with Generic Anafranil (Clomipramine HCL). 

Discuss the use of grapefruit products with your doctor before increasing or decreasing the amount of grapefruit products in your diet.Generic Anafranil (Clomipramine HCL) can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Generic Anafranil (Clomipramine HCL) can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun. 

Side effects of Generic Anafranil (Clomipramine HCL) 


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.Call your doctor at once if you have any of these serious side effects: chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;sudden numbness or weakness, especially on one side of the body;sudden headache, confusion, problems with vision, speech, or balance;feeling light-headed, fainting;fever, confusion, muscle stiffness, sweating, fast or uneven heartbeats;pale skin, easy bruising or bleeding, unusual weakness; orurinating more than usual.

Less serious side effects may be more likely to occur, such as:


nausea, vomiting, stomach pain, loss of appetite, constipation or diarrhea;dry mouth, unpleasant taste;increased appetite, weight changes;feeling anxious, restless, dizzy, drowsy, or tired;blurred vision, trouble concentrating;sleep problems (insomnia), nightmares;blurred vision;increased sweating; ordecreased sex drive, impotence, or difficulty having an orgasm.


What other drugs will affect Generic Anafranil (Clomipramine HCL)?


If you are using any of these drugs, you may not be able to use Generic Anafranil (Clomipramine HCL), or you may need dosage adjustments or special tests during treatment.There are many other medicines that can interact with Generic Anafranil (Clomipramine HCL). Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.